Difference between metacoder and aggregate results in differential analysis
Hello,
Reading the rANOMALY article (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7836088/), I have a question on the results between metacoder analysis and the aggregate one.
On fig. 6, we can see g__Enterobacteriaceae_genus which is more abundant with "Teat" (in green). On fig. 7, after aggregation of results, we can see this genus as more abundant with "Milk". We have the same with : Lactococcus, Sphingomonas, Lactobacillus, ...
As I reproduce the same situation with my own datas, I don't know if it's an issue or just I'm not understanding how the aggregation function works.
Thanks in advance for your response.