<pclass="description lead">D-GENIES – for Dotplot for Genomes Interactive, E-connected and Speedy – is an online tool
<pclass="description lead">D-GENIES – for <strong>D</strong>otplot large <strong>Gen</strong>omes in an <strong>I</strong>nteractive, <strong>E</strong>fficient and <strong>S</strong>imple way – is an online tool
designed to compare two genomes. It supports large genome and you can interact with the dot plot to improve the visualisation.</p>
<pclass="description">We use minimap version 2 to align the two genomes. Then, the PAF file is parsed and plotted into
an interactive plot written with d3.js library.</p>
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<p>Dot plots are widely used to quickly compare sequence sets. They provide a synthetic similarity overview, highlighting repetitions, breaks and inversions. Different tools have been developed to easily generated genomic alignment dot plots, but they are often limited in the input sequence size. D-GENIES is a standalone and WEB application performing large genome alignments using minimap2 software package and generating interactive dot plots. It enables users to sort query sequences along the reference , zoom in the plot and download several image, alignment or sequence files. D-GENIES is an easy to install open source software package (GPL) developed in Python and JavaScript.</p>