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# appinetwork
An R package for constructing and Analysing of Protein-Protein Interactions (PPI) NETWORKs for complexes and biological processes


## Installation

We assume that R, Python version 2.7 and C are installed, prior to any attempt to install the package appinetwork. 

To install this package from git, you need the devtools package using the following command in R :

    install.packages("devtools")
    library("devtools")
    
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You also need the to install the following packages :

    install.packages( pkgs = c("R.methodsS3","rPython","stringr","rlang", "igraph"), dependencies = TRUE)

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Now you can install our package from Gitlab using the following command in R :
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    devtools::install_gitlab("GNet/appinetwork", host = "https://forgemia.inra.fr")
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Installion on Windows and Mac Os might be more difficult : we advise to try the installation under R version 3.5.0.      
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    install.packages("devtools")
    library("devtools")
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    install.packages( pkgs = c("R.methodsS3","rPython","stringr","rlang", "igraph"), dependencies = TRUE)
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    devtools::install_gitlab("GNet/appinetwork", host = "https://forgemia.inra.fr")
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## Usage
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This package implements a function `interface()` which enables to format PPI databses and performs two mains analysis : model complexes assembly intermediaries and cluster PPI networks. The step by step procedure is described in the [userguide](https://forgemia.inra.fr/GNet/appinetwork/-/blob/master/userguide.pdf).
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## For more information : read the [userguide](https://forgemia.inra.fr/GNet/appinetwork/-/blob/master/userguide.pdf)
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